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CARAT (Chronic & Acute Risk Assessment)
CARAT (Chronic & Acute Risk Assessment) is a software dedicated to make the statistical methodologies for food risk assessment developed in INRA-Met@risk accessible to a wide range of researchers.
The first version of the software is fully described in the book (in French) Analyse des Risques Alimentaires, Chapitre 12 [Buche et al, 2006].
Authors
Patrice Buche, Computer scientist, Patrice.Buche@agroparistech.fr
Lydie Soler, Computer scientist, Lydie.Soler@agroparistech.fr
Jessica Tressou, Statistician, Jessica.Tressou@agroparistech.fr.
Technical details
CARAT is a Web application developed in Java programming language. The data managed by CARAT are stored in a Postgres database.
Databases
Originally (in version 1.1), CARAT uses two databases:
- Individual food consumption data from the INCA survey (Credoc-Afssa-Dgal, 1999). This provides the detailed quantities of food consumed by 3003 individuals over a week.
- Food contamination data provided by Met@risk partners (Dgal, etc.) or resulting from surveys conducted by Met@risk. This database is regularly updated with new data.
Statistical methodologies
Version 1.1 includes:
- A convivial interface to build the food groups entering into an exposure assessment computing various description statistics.
- The so-termed deterministic calculation of exposure to a contaminant, also called the distributional approach: this uses the consumption observations and aggregated measures of contamination such as mean, median.
- The non-parametric exposure assessment: this uses both the consumption and contamination observations
- Different options to deal with the left censorship of the contamination data (presence of non detects, or non quantified measures): nonparametric or deterministic.
- The possibility to compute the exposure for different time window (week, day).
See Tressou (2005) and Feinberg et al. (2006) for general description of the methodologies, Tressou et al. (2004a, 2004b) and Counil et al (2005) for examples of outputs, and Bertail & Tressou (2006), Tressou (2006) for left censorship treatments.
References
- Buche, P., Soler, L., & Tressou, J., 2006. Le logiciel CARAT. In : Feinberg M., Bertail P., Tressou J., Verger P., Analyse des Risques alimentaires, pp 305-333.
- Bertail, P. & Tressou, J., 2006, Incomplete generalized U-Statistics for food risk assessment. Biometrics 62 (1), 66-74
- Counil, E., Verger, P. & Volatier, J.L., 2005. Handling of contamination variability in exposure assessment : A case study with ochratoxin A. Food Chemical and Toxicology 43(10), 1541-1555.
- Counil, E., Verger, P. & Volatier, J.L., 2005. Fitness-for-purpose of dietary survey duration: a case study with the assessment of exposure to ochratoxin A. Food Chemical and Toxicology 44(4), 499-509.
- Credoc-Afssa-Dgal, 1999. INCA, Enquête nationale sur les consommations alimentaires, Tech & Doc. Lavoisier, Coordinateur: J.-L. Volatier.
- Feinberg, M., Bertail, P., Tressou, J., & Verger, P., 2006. Analyse des Risques alimentaires, Tec&Doc, Paris.
- Tressou, J., 2005. Méthodes statistiques pour l'évaluation du risque alimentaire. PhD thesis, University Paris X.
- Tressou, J., 2006. Non Parametric Modelling of the Left Censorship of Analytical Data in Food Risk Exposure Assessment. Journal of the American Statistical Association, A&CS, 101 (476), 1377-1386.
- Tressou, J., Crépet, A., Bertail, P., Feinberg, M. & Leblanc, JCh., 2004. Probabilistic exposure assessment to food chemicals based on extreme value theory: Application to heavy metals from fish and sea products. Food Chemical and Toxicology 42, 1349-1358.
- Tressou, J., Leblanc, JCh., Feinberg, M. & Bertail, P., 2004. Statistical methodology to evaluate food exposure to a contaminant and influence of sanitary limits: application to ochratoxin A. Regulatory Toxicology and Pharmacology 40, 252-263.
Writing:
Unité Mét@risk, P. Buche
Creation date: 23 October 2008
Update: 24 November 2011
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